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Fatigue after quitting nicotine occurs due to dopamine withdrawal, reduced stimulant effects, and temporary hormonal imbalances

Initial bivariate analyses indicated that open pressure drop, diameter, wet weight, and dry weight were associated with this outcome, but logistic modeling suggests that only open pressure drop was significantly associated (p=0.02), after controlling for other factors

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Between 2001/2002 and 2010/2011, young adult smoking declined significantly in six of the eight states in the highest price/expenditure tobacco control activity group and average prevalence in this group declined by 8.9 percentage points, from 23.0% (95% CI 21.6% to 24.5%) to 14.1% (95% CI 12.8% to 15.4%) (table 2)

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