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If the nicotine is intended for use in e-liquids, MHRA (Medicines and Healthcare Products Regulatory Agency) regulations will apply, particularly under the Tobacco and Related Products Regulations 2016
Another important limitation is that very few studies measured or adjusted for use of other substances (most importantly, perhaps, cannabis, which has been widely discussed as a potential risk factor for schizophrenia)
Each year the Guardian is a media partner of the Global Drug Survey and we are aiming for a record number of responses this year
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