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The simple answer is toxicity, but that answer doesnt provide the details intelligent bartenders are looking for, so in this post, Ive expanded on the question
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Among ever-smokers when compared to non-carriers of the CHRNA3 rs1051730 T-allele, age and sex adjusted HRs for risk of ulcerative colitis were 1.03(95%CI 0.891.18) in heterozygotes and 0.91(0.721.16) in homozygotes
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