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In Japan, annual tobacco consumption has decreased by nearly half from 3,393 grams in 1980 to 1,655 grams in 2015

Alternative tobacco and nicotine products have been introduced by the tobacco industry in response to the diminishing popularity of smoking

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Individuals on these medications should ask their provider about side effects, how to manage them, and whether adjustments are necessary if symptoms change

Also, earlier research showed that the users of HTP tend to be younger and more educated than the users of classic cigarettes [60]