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As proposed in 427.402(b)(4)(i), if the manufacturer believes there are multiple events causing severe supply chain disruptions during the same four calendar quarters for the same Part B rebatable biosimilar biological product and submits multiple rebate reduction requests for the same product, CMS will grant no more than one rebate reduction for that Part B rebatable biosimilar biological product for those 4 consecutive calendar quarters
Additionally, the Bayesian model for age-period-cohort was introduced to forecast the burden
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