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We previously reported that reduced levels of activated hepatocyte growth factor and the c-Met receptor tyrosine kinaseboth of which are vital for maintaining cellular redox balancecombined with increased expression of GJ proteins in hepsin-deficient mice

Sections were then incubated overnight at room temperature in primary antibodies diluted in PBS-T DS

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In terms of signaling, the transcription factor NF-B, which regulates TNF- expression, and AP-1, which regulates IL-4 expression, were suppressed