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Caffeine blocks adenosine receptors to reduce the sense of fatigue and raise arousal, and it has more controlled trials behind it than any other cognitive enhancer, which makes it the reliable choice for alertness and sustained attention

Folate, B12 And MTHFR MTHFR stands for methylene-tetra-hydro-folate reductase , an enzyme that reduces 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate

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