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Metagenomic analysis indicated enrichment in oxidative phosphorylation, arachidonic acid, and tryptophan metabolic pathways, as well as numerous GH109 family enzymes involved in mucin degradation 73

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Recent studies demonstrate that ferroptosis not only shapes innate and adaptive immune responses-including T and B lymphocytes, macrophages, neutrophils, and dendritic cells-but also remodels inflammatory microenvironments to either preserve tissue integrity or exacerbate damage