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While there are no strict dietary restrictions with semaglutide, adopting a balanced and healthy eating plan is recommended to maximize both weight loss and overall health benefits

Last reviewed: June 26, 2026 Last updated: June 26, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

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[DOI] [PMC free article] [PubMed] [Google Scholar] 167.Locatelli J.C., Costa J.G., Haynes A., Naylor L.H., Fegan P.G., Yeap B.B., Green D.J

These complementary receptor actions reduce appetite and energy intake, slow gastric emptying, and improve glucose regulation, which together drive steady weight loss