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Speculated biological plausibility for the sex difference include differences in body weight at baseline, which might lead to greater average drug exposures among women compared to men, and the potential interaction of semaglutide with sex hormones that play a role in appetite regulation (e.g., estrogen)

After surgery, both medications can slow digestion and cause nausea, bloating, or diarrhea

Surgical procedures provide more immediate outcomes, but newer surgical innovations and techniques are constantly evolving, offering a range of effective solutions

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4,5 The prevalence of overweight and obesity is a public health issue that has severe cost implications to healthcare systems