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Addressing these gaps will require well-designed longitudinal studies and pediatric-specific clinical trials to establish the safety, durability, and optimal positioning of incretin-based therapies in adolescent obesity management

It is known for its role in skin pigmentation, appetite regulation, and immune modulation

BDNF potentiates excitatory synapses via pre- and post-synaptic mechanisms [22, 23]

NSS was significantly lower in the BDNF-NSC-transfected transplant group compared to the control groups for the 10-week time period (72)