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The relation between DPP4/CD26 expression and site of CoVs-related injuries is overall well demonstrated in MERSCo-V infection, where DPP4 could directly influence the kinetic of lung inflammation and may act itself as a proinflammatory signaling molecule [16, 18]

The issue is proceeding without a clear clinical framework for sequencing, inflammation control, and tissue readiness

doi: 10.1111/ene.12297 189 RubegniA.BattistiC.TessaA.CeraseA.DocciniS.MalandriniA.et al

This makes IGF-1 LR3 important in study models where reduced IGFBP association is the main point of interest

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