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While the market is highly attractive to manufacturers, companies who aim to successfully commercialize therapies face a steep task: shifting sands necessitate carefully constructed development programs and product strategies

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Cobalamins circulate bound to serum proteins called transcobalamins (TC) and haptocorrins

Astaxanthin targets PI3K/Akt signaling pathway toward potential therapeutic applications

For example, a large expansion of the astacin protease and CAP gene families coincided with the emergence of parasitism in the animal parasitic Strongyloides nematodes [10] whilst gene duplication is proposed to have been an important driver of parasitism in the Orobanchaceae plant parasites [11]