Reviews on the topic highlight that while clinical trials are essential to ensure a drug's safety and performance prior to widespread (routine) administration, their inherent rigidity in participant selection leaves critical gaps regarding how these medications perform in routine clinical practice, especially among elderly or frail patients and similar high-risk populations
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Intramuscular injection causes semaglutide to absorb much faster than intended, which can increase side effects like bloating , dizziness , and fatigue while potentially reducing the duration of the medication effect between doses
[DOI] [PMC free article] [PubMed] [Google Scholar] 69.Peng Y., Yao S.Y., Chen Q., Jin H., Du M.Q., Xue Y.H., Liu S
Once diabetes is diagnosed, holistic management of organ protection targeting MDS should be provided since most patients with T2D also have MDS