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VGF is a neurosecretory protein that primarily functions via its downstream proteoforms, with putative roles in metabolic regulation, A clearance and synaptogenesis 48,49,50

Oswaldo Cruz 84 (Suppl 1), 3137 (1989)

At the conclusion, the participants had lower levels of reactive oxygen species and suppressed expression of the pro-inflammatory cytokines TNF-alpha and IL-6

10.1186/s12967-025-06300-0 Summary Keywords exercise, ferroptosis, neurodegenerative disease, exerkine, iron metabolism Citation Tang S, Zhang J, Chen J, Zhou Z and Lin Q (2025) Ferroptosis in neurodegenerative diseases: potential mechanisms of exercise intervention

PBMCs were maintained in RPMI supplemented with FCS (10%) and penicillin-streptomycin (1%)