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FDA-approved formulations for semaglutide as Ozempic and Wegovy use milligrams and are sold as self-administered injectable pens with a set dosage

Side effects are usually mild, like redness or tenderness at the injection site, and they disappear quickly

Microscopically, airway inflammation, edema, and hemorrhage were shown as well as pericentral necrosis

If a patient takes both medications daily via pen injections, distinguishing between them becomes harder without understanding the underlying pharmacology

It goes further to explain that the gastric peptide ghrelin is also a potent GH secretagogue that can amplify GHRH secretion, leading to higher growth hormone levels, as seen in the figure below